Acylation of β-Keto Ester with Acyl Chloride Using Aluminum Chloride
نویسندگان
چکیده
منابع مشابه
A direct reduction of aliphatic aldehyde, acyl chloride, ester, and carboxylic functions into a methyl group.
The aliphatic carboxylic group was efficiently reduced to the methyl group by HSiEt(3) in the presence of catalytic amounts of B(C(6)F(5))(3). To the best of our knowledge, this is the first example of a direct exhaustive reduction of aliphatic carboxylic function. Aliphatic aldehydes, acyl chlorides, anhydrides, and esters also underwent complete reduction under similar reaction conditions. Ar...
متن کاملTin(II) chloride assisted synthesis of N-protected γ-amino β-keto esters through semipinacol rearrangement.
A facile synthetic route for the preparation of N-protected γ-amino β-keto esters from amino aldehydes and ethyl diazoacetate is described. The two component coupling is facilitated by tin(II) chloride followed by semipinacol rearrangement leading to the product in quantitative yield. The reaction is mild, instantaneous and compatible with Boc-, Fmoc- and Cbz-amino protecting groups.
متن کاملRearrangement/Fragmentation Reactions of Oligosilanes with Aluminum Chloride
Reinvestigation of the Lewis acid catalyzed rearrangement of some open-chain permethyloligosilanes with the Al(Fe)Cl(3) catalyst system exhibited several cases of additional reactivity: namely, a fragmentation/cyclization reaction. Introduction of (trimethylsilyl)methyl substituents into the oligosilane substrates strongly facilitated this reaction, yielding cyclic or bicyclic carbacyclosilanes...
متن کاملEffect of combined administration of Zinc chloride and Aluminum chloride on memory and motor activity of young rats
Introduction: Aluminum is known as a neurotoxic element which causes neurodegeneration, learning deduction and movement disorders. Aluminum ions in the brain cause serious problems such as Alzheimer, Parkinson and other degenerative diseases. On the other hand, Zinc is a dietary element essential for several biological processes, modulates neurotransmission in brain regions and associates wi...
متن کاملEffects of Aluminum chloride (AlCl3) on spatial memory: association with oxidative stress
The effects of chronic AlCl3 exposure on spatial memory in rats remain controversial. Since some toxic metals such as aluminum when entered the body, can contribute to diseases such as Alzheimer, in this study the time course effect of the systematically administered AlCl3 on the spatial memory retention in the Morris Water Maze was investigated. Rats were treated with AlCl3 (1 gr/lit) for two,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1966
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.87.8_880